Substituted imidazopyridine derivatives as melanocortin-4 receptor antagonists

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专利权人:

Hol;Barbara Hoffmann-Enger;Marco Henneböhle;Ulrich Abel;Sonja Nordhoff;Holger Deppe;Michael Soeberdt;Inge Ott;Miroslav Terinek;Philipp Weyermann;Achim Feurer;Günther Metz;Hervé Siendt;Christian Rummey

发明人:

Günther Metz,Holger Deppe,Ulrich Abel,Achim Feurer,Inge Ott,Sonja Nordhoff,Michael Soeberdt,Barbara Hoffmann-Enger,Philipp Weyermann,Hervé Siendt,Christian Rummey,Miroslav Terinek,Marco Henneböhle,Hol

申请号：

US12530676

公开号：

US08236818B2

申请日:

2008.03.28

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to substituted imidazopyridine derivatives as melanocortin-4 receptor (MC-4R) modulators, in particular as melanocortin-4 receptor antagonists. The antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, amytrophic lateral sclerosis (ALS), anxiety and depression.

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