METHOD AND PROCESS FOR QUANTITATIVE EVALUATION OF PHARMACOKINETICS, THERAPEUTIC EFFECTS AND SAFETY OF DELIVERY OF DRUG COMPOUNDS TO THE INNER EAR FOR TREATMENT OF AUDITORY DISEASE
The Charles Stark Draper Laboratory, Inc.;Massachusetts Eye and Ear Infirmary;Massachusetts Institute of Technology
发明人:
Jeffrey T. Borenstein,Erin Pararas,Ernest S. Kim,Vishal Tandon,Andrew Ayoob,Michael McKenna,William Sewell,Marcello Peppi,Marc Weinberg,Robert Langer
申请号:
US15631933
公开号:
US20180000956A1
申请日:
2017.06.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure provides compositions and methods for treating an auditory disease in a subject in need thereof comprising administering an effective amount of a gel-based precursor that includes an inner ear-specific therapeutic compound directly into the cochlea of the subject.