Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
Guzzo, Peter R.,Henderson, Alan J.,Isherwood, Matthew,Lee, Chong Yew,Ghosh, Animesh,Zhao, He River
申请号：
AU2012207335
公开号：
AU2012207335A1
申请日:
2012.01.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT6) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I) with the substituents being described herein.
