A cystostomy device for implant in a patient includes a transcutaneous sleeve a flange connected to the transcutaneous sleeve, adapted to reduce contamination of an outer surface of said transcutaneous sleeve, a catheter defining a passage for the flow of fluids from within the patient to outside the patient, an inner surface of the transcutaneous sleeve defining a path through which the catheter passes, and an anchor adapted for implantation into the biological tissue of the patient, the anchor connecting to the catheter and the transcutaneous sleeve. At least one microbe resistance zone is included on surfaces in any of the sleeve, the flange, and the catheter. The microbe resistance zone may be formed on the surfaces of the sleeve, flange and catheter, or may be adhered to the device as tape that may be rolled. A micropore filter prevents back flow of urine from a urinary bag.