Edward I. Ginns,Marzena Galdzicka,Janice A. Egeland
申请号:
US14862861
公开号:
US10143684B1
申请日:
2015.09.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods for treating and diagnosing psychiatric affective disorders, e.g., an affective disorder associated with aberrant Sonic Hedgehog (Shh) signaling, by administering to the subject a therapeutically effective amount of an antagonist to Smoothened (Smo), an antagonist to Patched-1 (Ptch-1) and/or an antagonist to Shh.