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"vector, substantially isolated nucleic acid molecule, host cell, pharmaceutical composition, use of a nucleic acid molecule, use of a vector, use of a host cell, and use of a composition"
专利权人:
TRANSGENE S.A.
发明人:
DORIS SCHMITT,NATHALIE SILVESTRE
申请号:
BRPI0810305
公开号:
BRPI0810305A2
申请日:
2008.01.29
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention provides a vector for expressing at least a first and a second nucleic acid molecules which exhibit a percentage of homology of approximately 80% or greater than 80% over a portion of 40 or more continuous nucleotides and wherein said first nucleic acid molecule and/or said second nucleic acid molecule is modified so as to reduce said percentage of homology to less than 75%. The present invention also relates to substantially isolated nucleic acid molecules comprising a nucleotide sequence as defined in any of SEQ ID NO: 9-15 and 66-69. It also provides a host cell and a pharmaceutical composition comprising such a nucleic acid molecule or vector as well as their use for therapeutic or preventive purposes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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