One embodiment of the present invention sets forth a technique for operating an oxygen concentrator. The technique includes measuring a product gas within an oxygen concentrator to produce a product gas measurement, and determining that an output of the oxygen concentrator is fluidly connected to a respiratory ventilation device based on the product gas measurement. The technique further includes, in response to determining that the oxygen concentrator is fluidly connected to the respiratory ventilation device, determining that the output of the oxygen concentrator does not meet a supply gas requirement of the respiratory ventilation device and, in response to determining that the output of the oxygen concentrator does not meet the supply gas requirement, adjusting a control output in the oxygen concentrator to modify operation of the oxygen concentrator.