Kunio SHIOTA,Koji HAYAKAWA,Mitsuko TAKAMORI,Ryosuke FUJII,Yukishige ITO
申请号：
US15564030
公开号：
US20180085385A1
申请日:
2016.04.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides an agent containing N-acetyl-D-mannosamine for protecting a glucose-sensitive cell from glucose toxicity due to high glucose concentration； a pharmaceutical composition for protecting a glucose-sensitive cell from glucose toxicity due to high glucose concentration, containing an effective amount of N-acetyl-D-mannosamine and a pharmaceutically acceptable carrier； use of N-acetyl-D-mannosamine in producing a medicament for protecting a glucose-sensitive cell from glucose toxicity due to high glucose concentration； and a method of protecting a glucose-sensitive cell from glucose toxicity due to high glucose concentration, including administering an effective amount of N-acetyl-D-mannosamine to a subject in need thereof. The glucose-sensitive cell is selected from the group consisting of a nerve cell, a renal cell and a vascular endothelial cell.
