This invention provides a toothbrush device comprising: a plurality of bristle tuft assemblies, every the bristle tuft assembly comprises a support member and a bristle tuft, the bottom of which is flexibly configured within the support member; a base, a plurality of assembly holes are configured on the base, support members of the plurality of bristle tuft assemblies are flexibly configured in the plurality of assembly holes respectively; a supportive rotating axis, fixedly connecting with an axis hole in the back of the base and driving the base rotate back and forth; a back shell, a housing chamber matching in size with and accommodating the base is configured on the back shell, the supportive rotating axis is rotationally connected with the back shell. The toothbrush device can more effectively and easily clean the teeth, and different bristle tufts can move independently in different directions in accordance with the irregular surface shapes of teeth so that teeth surface and seams can be much more thoroughly and efficiently cleaned.