Compositions and methods for treating or preventing endocrine FGF-linked diseases

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专利权人:

Yale University

发明人:

SCHLESSINGER, Joseph,LEE, Sangwon

申请号：

AU2018297285

公开号：

AU2018297285A1

申请日:

2018.07.05

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present invention relates in one aspect to the discovery that β-Klotho is the primary cell-surface receptor for FGF21, with FGFR1c functioning as a catalytic subunit that ultimately mediates intracellular signaling. In one aspect, the invention provides compositions and methods that are useful in treating or preventing endocrine FGF-related diseases or disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/