A composition, a method of manufacture, and a method of application for the treatment of arthritis, skeleton-muscular joint inflammation, and certain skin conditions. The composition comprises a mixture of diphenhydramine, caffeine, magnesium, and petrolatum mixed to form an ointment for application to the affected part of the body. The method of application includes the use of a wet porous membrane, such as a wet paper towel, covering the applied ointment on the skin for a period of time after application.