The invention concerns a method for obtaining operating parameters for an x-ray CBCT imaging apparatus in view of acquiring a set of data of a patient's maxillofacial region. The method comprises: —;identifying a patient's maxillofacial first region of interest (ROI1), —;determining a height of a horizontal plane of said patient's maxillofacial first region of interest (ROI1) when the patient is in an occlusion position or bites a patient positioning accessory, —;acquiring through a slit-shaped collimator window a first set of data relative to said patient's maxillofacial first region of interest (ROI1) including the horizontal plane using x-ray CBCT imaging, —;reconstructing an axial CBCT slice comprising the horizontal plane based on the first set of data relative to the reconstructed the patient's maxillofacial first region of interest (ROI1), —;displaying the reconstructed axial CBCT slice of the patient's maxillofacial first region of interest (ROI1) from the acquired first set of data, —;defining at least partially a second region of interest (ROI2) based on the displayed reconstructed axial CBCT slice of the patient's maxillofacial first region of interest (ROI1) and intersecting the latter, —;obtaining operating parameters for an x-ray CBCT imaging apparatus based on at least the defined second region of interest (ROI2) in view of acquiring a second set of data including the defined second region of interest (ROI2).