Hyun Yong Lee;Hyun Sik Choi;Hyung Bok Lee;Joobyoung Yoon;Hwan Bong Chang
发明人:
Hwan Bong Chang,Joobyoung Yoon,Hyun Yong Lee,Hyun Sik Choi,Hyung Bok Lee
申请号：
US14007603
公开号：
US20140018552A1
申请日:
2012.03.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides an AGE inhibitor and a health functional food for inhibiting an occurrence of diabetic complications. Particularly, the present invention comprises a compound selected from the group consisting of mulberrofuran G, mulberrofuran K, kuwanon G, kuwanon Z, oxyresveratrol, 2′,4′,5,7-tetrahydroxyflavanone, morusignin L and dihydromorin isolated from Morus Bark as an active ingredient. The compounds disclosed above inhibit the production of AGE which is a causative substance of diabetic complications. Thus, the compounds could be used as an AGE inhibitor and a health functional food for inhibiting diabetic nephropathy, diabetic retinopathy and diabetic neuropathy.
