The present invention relates to glucocorticoid-containing pharmaceuticalcompositions or kits for use in acute emergency situations where acuteglucocorticoid therapy is required. Notably, the invention relates topharmaceutical compositions and kits that are designed to be administered bynon-medically trained persons outside a hospital or another medical orclinical setting. The invention also relates to a method for treating adisorder requiring acute glucocorticoid therapy by providing a fast onset ofaction of a glucocorticoid