Conn, P. Jeffrey,Lindsley, Craig W.,Stauffer, Shaun R.,Jones, Carrie K.,Conde-Ceide, Susana,Tong, Han Min,Bartolome-Nebreda, Jose Manuel,MacDonald, Gregor James
申请号:
AU2011338339
公开号:
AU2011338339A1
申请日:
2011.12.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
In one aspect, the invention relates to bicyclic pyrazole compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.