Methods and systems are provided for harvesting at least a portion of a blood vessel, such as the radial artery in the upper extremity and the saphenous vein in the lower extremity. In certain embodiments, an endoscopic surgical system includes a blunt tip trocar (BTT) for insertion into an incision in the extremity, a cannula for insertion through the BTT, a bisector/bipolar device, and an endoscope. The endoscope may have a dissection tip at its distal end for dissecting tissue from the blood vessel and, with the tip removed, may provide a visual field at its distal end. The endoscope is sized to fit into the cannula and provides visualization of the blood vessel during bisection with the bisector/bipolar device.