Jaenisch Rudolf,Hanna Yaqub,Wernig Marius,Lengner Christopher J.,Meissner Alexander,Brambrink Oliver Tobias,Welstead G. Grant,Foreman Ruth
申请号:
US201715607028
公开号:
US10093904(B2)
申请日:
2017.05.26
申请国别(地区):
美国
年份:
2018
代理人:
Warren, Esq. Lisa M.`Morse, Barnes-Brown & Pendleton, P.C.
摘要:
The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells.