It is 0. that provide a kind of aqueous ophthalmic solution, which include the concentration of hyaluronic acid or its salt,03-0.5% (weight/volume), PG concentration 0.1-1.0% (weight/volume), benzalkonium chloride concentration 0.001-0.002% (weight/volume) is used as preservative and tonicity agent ion with such concentration, so that the ophthalmic solution of osmotic pressure ratio becomes 0.9-1.1. Preferred ionic agents include sodium chloride, calcium chloride and magnesium chloride. This programme is suitable for treating the eye that do not cry.