The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof.Linvention concerne des procédés dutilisation de thérapies en combinaison contenant le [2-({4-[(diméthylamino)iminométhyl]phényl}carbonylamino-5-méthoxyphényl]-N-(5-chloro(2-pyridyl)carboxamide pour le traitement de pathologies thrombotiques et des compositions pharmaceutiques de celles-ci.