Ocular highly ophthalmic solution and fluorescent imaging agents and methods for their preparation

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专利权人:

国立大学法人大阪大学

发明人:

西田 幸二,馬場 耕一,笠井 均,田中 佑治,久保田 享,横倉 俊二

申请号：

JP2010536777

公开号：

JP5709523B2

申请日:

2009.11.04

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

Disclosed is an eye drop which can achieve high intraocular migration of a medicinal agent contained therein without the need of any carrier such as a liposome.  Also disclosed is a method for producing the eye drop. The eye drop is characterized by comprising particles composed of a hydrophobic or liposoluble prodrug that can become hydrophilic or water-soluble upon hydrolysis, wherein the particles have a particle size of not smaller than 10 nm and smaller than 1 µm.

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中国工程科技知识中心

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