Beth Israel Deaconess Medical Center;Los Alamos National Security, LLC
发明人:
申请号:
EP09828172.8
公开号:
EP2358757B1
申请日:
2009.11.18
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.