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Inhibitors of SOX18 protein activity for treating angiogenesis- and/or lymphangiogenesis-related diseases
专利权人:
The University of Queensland
发明人:
Francois, Mathias,Zuegg, Johannes,Overman, Jeroen,Mamidyala, Sreeman Kumar,Salim, Angela Aguslyarti,Fontaine, Frank Roger,Cooper, Matthew Allister,Capon, Robert John,Robertson, Avril Alexis Barbara
申请号:
AU2017383102
公开号:
AU2017383102A1
申请日:
2017.12.21
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Disclosed are compounds of a formula provided herein that show efficacy in the inhibition of SOX18 protein activity, and in particular with respect to the ability of SOX18 to bind DNA and/or particular protein partners. Further, methods of treating angiogenesis- and/or lymphangiogenesis-related diseases, disorders or conditions, such as cancer metastasis and vascular cancers, are provided herein.
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