An endoluminal surgery system is disclosed. The endoluminal surgery system includes an operating device, a connecting rod, and a handle. The operating device includes an operating part and a connecting part. During the surgery, the operating device is placed in a body cavity through an incision, and then a piercing end of the connecting rod enters the body cavity through a piercing point and is fixedly connected with the connecting part of the operating device. The other end of the connecting rod that is outside the body is fixedly connected with the handle. Next, the operating part is controlled through the handle outside the body to achieve the corresponding surgical operation. After the operation, cut off the connecting rod, take out the operating device from the incision, and pull out the connecting rod, leaving no wound or tiny wounds on body. The present disclosure can reduce the injury to the patient's body, and make the surgical operation outside the body cavity more convenient, and improve the success rate of the operation.
