Jin Chul KIM,Ju Hyup LEE,Kyeong Nan KWON,Dong Youl YOON,Hong ZHANG
申请号：
US15067151
公开号：
US20170100484A1
申请日:
2016.03.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed is a drug delivery carrier for sustained release of medicinal protein. The drug delivery carrier has an effect of efficiently loading medicinal proteins that are positively charged at a pH value of an isoelectric point or less of the medicinal proteins, based on electrostatic attraction. In addition, the drug delivery carrier releases medicinal proteins under human physiological conditions (pH 7.4, 37° C.) based on electrostatic repulsion and more specifically, has an effect of sustainedly releasing medicinal proteins for a long time between heat-sensitive polymer layers condensed due to body temperature.
