The present invention relates to a particle or pharmaceutical composition comprising one, more particles or a suspension of same or different particles comprising a degradable compound and an alpha emitting radionuclide and/or a radionuclide generating alpha emitting daughter. A particle comprising CaCO3, the alpha emitting radionuclide 224Ra, and a 224Ra radionuclide progeny is in particular disclosed. The particles are beneficial for use in the treatment of cancer.
