The present invention relates to equipment and a method for manufacturing a vacuum blood collecting tube and, more specifically, to equipment and a method for manufacturing a vacuum blood collecting tube having a crack test device and a reagent spray device, which removes the defect rate of a vacuum blood collecting tube by testing whether the vacuum blood collecting tube for storing collected blood and separating the constituents of the collected blood is cracked, uniformly sprays a reagent for promoting the constituent separation of the blood, and uniformly maintains the inner vacuum degree of each vacuum blood collecting tube. The equipment for manufacturing a vacuum blood collecting tube comprises: a cartridge in which the vacuum blood collecting tubes are aligned; a reagent spray device which supplies a reagent to the vacuum blood collecting tubes; a drying device which dries the vacuum blood collecting tubes coated with the reagent; a crack test device which tests whether the vacuum blood collecting tubes are cracked; a vacuum chamber which seals the caps of the dried vacuum blood collecting tubes, a transfer device which successively moves the cartridge; and a control part.본 발명은 진공채혈관의 제조설비 및 제조방법에 관한 것으로, 더 상세하게는 채취된 혈액을 저장하면서 성분을 분리시키는 진공채혈관의 튜브 균열여부를 검사하여 진공채혈관의 불량률을 제거하고, 혈액성분의 분리를 촉진시키는 시약의 도포가 균일하게 이루어지도록 하고, 각 진공채혈관 내부의 진공도를 균일하게 유지시킬 수 있는 균열검사장치와 시약투입장치가 구비된 진공채혈관의 제조설비 및 제조방법에 관한 것이다.