An ultrasound delivery system can include a console assembly having a display and a computer system, and a positioning assembly operatively connected to the console assembly. The positioning assembly can be articulable between a plurality of different configurations upon receipt of one or more instructions from the computer system. The positioning assembly can include at least one gripper mechanism configured to selective grip and release. At least one probe assembly can include an ultrasound transducer assembly, a first bolus assembly and a second bolus assembly. The first bolus assembly can have at least a different geometry than the second bolus assembly. At least a portion of the ultrasound transducer assembly can be removably positionable within each of the first bolus assembly and the second bolus assembly. At least a portion of the probe assembly can be selectively connected to gripper mechanism and moved by the positioning assembly.