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人源化抗 PSA 的 5A10 抗體
专利权人:
Fredax AB
发明人:
TRAN, Amanda Thuy,AXELSSON, Anders,MALMBORG HAGER, Cecilia Ann-Christin,SJÖSTRÖM, Kjell,STRAND, Sven-Erik,LAMMINMÄKI, Urpo Juhani
申请号:
HK19101041
公开号:
HK1258674A1
申请日:
2019.01.21
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
The present invention provides antibody polypeptides with binding specificity for prostate specific antigen (PSA), wherein the antibody polypeptide comprises (a) a heavy chain variable region comprising the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 and SEQ ID NO:3 and/or (b) a light chain variable region comprising the amino acid sequences of SEQ ID NO:4 and SEQ ID NO:5 and SEQ ID NO:6, and wherein the heavy chain variable region and light chain variable region comprise framework amino acid sequences from one or more human antibodies. The invention further provides use of said antibody polypeptides in the diagnosis and treatment of prostate cancer
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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