An apparatus for therapeutic treatment with electromagnetic waves comprising a control circuit configured for generating a signal to be transmitted to an antenna for the generation of electromagnetic waves. The signal comprises a plurality of base pulses grouped in pulse packets and pulse trains, where each pulse packet consists of a series of base pulses followed by a first pause, and where each pulse train consists of a series of pulse packets followed by a second pause. In particular, the control circuit is configured for reversing the polarity of the base pulses after a given time interval.