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Inositol pyrophosphates, and methods of use thereof
专利权人:
Konstantina C. Fylaktakidou;Yves Claude Nicolau;Jean-Marie Lehn;Ruth Greferath
发明人:
Yves Claude Nicolau,Jean-Marie Lehn,Konstantina C. Fylaktakidou,Ruth Greferath
申请号:
US13024922
公开号:
US08178514B2
申请日:
2011.02.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.
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