Collapsible orthopedic fixation assemblies and related methods are disclosed. A collapsible fixation assembly includes end frames that are coupled with one or more cross beams. The fixation assembly is reconfigurable between a collapsed configuration in which the end frames are substantially aligned with the one or more cross beams and a deployed configuration in which the end frames are oriented transverse to the one or more cross beams and in which relative movement between the end frames and the one or more cross beams can be inhibited. The fixation assembly is configured to support at least one bone-interface component, which is configured to constrain a bone of a patient. In the collapsed configuration, the fixation assemblies is more compact than in the deployed configuration, thereby making it more easy to store and transport as compared to a comparable non-collapsible fixation assembly.