A biopsy needle guide, which has at least two degrees of freedom and can be freely positioned at least in a plane, includes a through-passing opening for passing a biopsy needle through. In an interior of the opening, a fixing structure and a clamping structure are present, and an adapter sleeve is present, which has a continuous opening for passing a biopsy needle through, as well as a stop collar, and which can be pushed into the opening as far as the collar and is rotatable after pushing in as far as the stop. By rotating the adapter sleeve to a first angle at most, a latch structure of the adapter sleeve engages behind the fixing structure of the opening, so that the adapter sleeve is fixed in the axial direction. By rotating the adapter sleeve beyond the first angle, the latch structure interacts with the clamp structure such that a biopsy needle that is introduced in the opening is fixed in the axial direction.