Cosmetic composition for skin rejuvenation and method and corresponding uses. Cosmetic composition for skin rejuvenation (? antiaging?) comprising a precursor of retinoic acid from the group consisting retinaldehyde, retinol, retinyl retinoate and retinyl esters, and melatonin. The invention also relates to a method for skin rejuvenation, and some uses of these compositions. The cosmetic composition has the equivalent efficacy of a pharmaceutical product comprising retinoic acid, but is free from side effects. The addition of other groups of substances, such as antiinflammatory drugs (such as licorice extract, alpha bisabolol, azulene, glycyrrhetinic acid, aloe vera extract and extract of Rosmarinum officinalis), antioxidants (such as green tea extract, resveratrol and ellagic acid ) and vitamins (like vitamin E and vitamin C), all approved for use in cosmetics, enhance the action? antiaging? of the composition.