CATRON NATHANIEL U S A,FICKES MICHAEL U S A,FISCHER CRISTINA U S A,HAIGHT ANTHONY R U S A,HEEMSTRA KATHERINE U S A,SANZGIRI YESHWANT U S A,SCHMITT ERIC U S A,TONG PING U S A,ZHANG GEOFF U S A,ZHOU DEL
申请号:
IN7760/DELNP/2011
公开号:
IN2011DN07760A
申请日:
2011.10.10
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
An orally deliverable pharmaceutical composition comprises a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.