The State of Oregon Acting by and through the State Board of Higher E
发明人:
Shawn Lockery
申请号：
US13673611
公开号：
US20130118411A1
申请日:
2012.11.09
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed herein are devices, systems, and methods for measuring an electropharyngeogram (EPG) in living organisms. In some embodiments, the devices and systems disclosed herein include an array for sorting and immobilizing an organism (such as a nematode) for measurement of an EPG and/or optical imaging. Also disclosed are methods for identifying therapeutic or toxic compounds utilizing the disclosed devices and systems. In some embodiments, the methods include screening for compounds with anthelmintic activity, toxicity (for example HERG channel blockers), or candidate drugs for treatment of a variety of human and/or animal diseases.
