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MOLECULE DE LIAISON A UN ANTIGENE REDIRIGE VERS UN LYMPHOCYTE T POUR CELLULES PRESENTANT UNE FONCTION D'IMMUNOSUPPRESSION
专利权人:
CHUGAI SEIYAKU KABUSHIKI KAISHA;OSAKA UNIVERSITY
发明人:
IGAWA, TOMOYUKI,ISHIGURO, TAKAHIRO,SAKAGUCHI, SHIMON,NISHIKAWA, HIROYOSHI
申请号:
CA2947157
公开号:
CA2947157A1
申请日:
2015.05.13
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides an antigen-binding molecule that exhibits an excellent antitumor effect greater than exhibited by conventional antigen-binding molecules, as a result of the antigen-binding molecule: cross-linking T cells and cells having an immune response suppressing function; and inducing damage to the cells having the immune response suppressing function. The antigen-binding molecule includes: a domain (1) that binds to molecules expressed on the surface of cells having the immune response suppressing function; and a domain (2) that binds to a T cell receptor complex.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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