The invention provides a pharmaceutical composition for use in a method for preventing, treating, ameliorating or managing cancer or a neoplastic disorder, or for preventing or treating cachexia, wherein the composition comprises an isolated peptide and a pharmaceutically acceptable carrier, wherein the isolated peptide has a length of 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28 or 29 amino acids, and wherein the peptide comprises the amino acid sequence of WEHVNAIQEARRLL (SEQ ID NO: 114), or the amino acid sequence WEHVNAIQEARRLL (SEQ ID NO: 114) comprising one or two conservative or non-conservative amino acid substitutions or amino acid equivalents.
