Zhang, Jiancun,Zhang, Yingjun,Zhang, Weihong,Liu, Bing,Zhang, Jiquan,Liu, Jinlei,Zhang, Lu
申请号:
AU2012339499
公开号:
AU2012339499A1
申请日:
2012.11.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter-and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.