Embodiments of the present disclosure relate to an electrode device to acquire, process and transmit physiological signals. The device eliminates the need for inconvenient wires attached at different locations on patients body. The device comprises a sensor patch comprising plurality of sensors/electrodes, configured to be in contact with a skin surface of a human body, to measure physiological of the patient. Also, the device comprises a wire-free module, embedded in the sensor patch, comprising an auto-orientation module to detect the orientation of the sensor patch on the human body using a plurality of sensors. The wire-free module comprises a processing module to process one or more signals received from the plurality of sensors/ electrodes. Further, the wire-free module comprises a detection module to detect one or more processed signals as a predefined physiological signal and a transmission module to transmit the detected physiological signal to a mobile device.