Inhibiteurs de la prostaglandine E2 synthase microsomale

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

申请号：

EP10765442.8

公开号：

EP2491007B1

申请日:

2010.10.14

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

This invention relates to compounds of formula I, their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions such as inflammatory/nociceptive pain. A, M, R1, R2, R7, Ra, Rb, Q3, Q4, Q6, Z2, Z4, Z5, Z6 and W have meanings given in the description.

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