Thomas D. Bannister,HUI Wang,Chao Wang,John L. Cleveland
申请号：
US15545117
公开号：
US20180009792A1
申请日:
2016.01.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides compounds effective as inhibitors of monocarboxylate transporters such as MCT1 and MCT4, which can be used for treatment of medical conditions wherein treatment of the condition with a compound having an inhibitor effect on MCT1, MCT4, or both is medically indicated. Compounds of the invention can have antitumor, antidiabetes, anti-inflammatory, or immunosuppressive pharmacological effects, and can be effective for treatment of cancer and of type II diabetes.
