A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target individual providing at least one classifier generated according to an analysis of a plurality of respective historical blood test results of each of another of a plurality of sampled individuals and evaluating using a processor a gastrointestinal cancer risk of the target individual by classifying the set of features using the at least one classifier.
