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PROCÉDÉ DE CRIBLAGE D'AGENT ANTIDIABÉTIQUE METTANT EN OEUVRE UN FACTEUR DE RÉGULATION DE LA SÉCRÉTION D'INSULINE NOUVELLEMENT IDENTIFIÉ
专利权人:
TOKYO INSTITUTE OF TECHNOLOGY
发明人:
IMAI, TAKESHI,HANDA, HIROSHI
申请号:
EP11821972
公开号:
EP2612678A4
申请日:
2011.09.02
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
It is an object of the present invention to provide a newly identified insulin secretion regulation factor that can control blood sugar in the normal range, and a method for screening an antidiabetic drug using said factor. In accordance with the present invention, there is provided a composition which is (i) a protein comprising an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4; or (ii) a protein comprising an amino acid sequence in which one or several amino acids are deleted, substituted or added in an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4 and negatively regulating insulin secretion, as well as a method for screening antidiabetic drug using said protein or a nucleic acid encoding the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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