The presently disclosed subject matter provides a solid immediate releasepharmaceutical particulate dosage form containing one population ofparticulates, and/or asolid immediate release pharmaceutical multi-particulate dosage formcontaining at least twodifferent populations of particulates. In certain embodiments, the immediatereleasepharmaceutical dosage forms contain at least three different populations ofmulti-particulates.Each population of particulates is designed for a specific function toaccomplish the desiredcombination of abuse deterrence and overdose protection.