The General Hospital Corporation;President and Fellows of Harvard College
发明人:
Alexander-Bridge, Maria,Sinclair, David A.
申请号：
AU2006266125
公开号：
AU2006266125B2
申请日:
2006.06.28
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.
