CD123 SPECIFIC CHIMERIC ANTIGEN RECEPTORS FOR CANCER IMMUNOTHERAPY

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专利权人:

发明人:

GALETTO ROMAN

申请号：

IN201617028258

公开号：

IN201617028258A

申请日:

2016.08.19

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention relates to Chimeric Antigen Receptors (CAR) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward selected membrane antigens and more particularly in which extracellular ligand binding is a scFV derivedfrom a CD123 monoclonal antibody conferring specific immunity against CD123 positive cells. The engineered immune cells endowed with such CARs are particularly suited for treating lymphomas and leukemia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/