NOVEL PEPTIDE FOR AUGMENTING AND EXPRESSION OF BDNF AND PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES INCLUDING ALZHEIMERS DISEASE OR PARKINSONS DISEASE, COMPRISING THE SAME
Kil Lyong Kim,Hong Gi Kim,Woo Ram Jung,Dong Ik Park,Min Kyoo Shin
申请号：
US12934029
公开号：
US20120208747A1
申请日:
2009.12.31
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are peptides for augmenting the expression of BDNF (brain-derived neurotrophic factor) and a pharmaceutical composition for the prevention and treatment of Alzheimers disease or Parkinsons disease, comprising the same. The peptides can induce the expression of BDNF in dopamine-reactive human cells, pass easily through the blood-brain barrier thanks to their low molecular weights and are almost free of cytotoxicity. Thus, they are useful in the prevention and treatment of neuropathies such as Alzheimers disease or Parkinsons disease.
