LINN, MICHAEL,SCHMITZ, CHRISTOPH,FRANKE, HANSHERMANN
申请号：
CA3086494
公开号：
CA3086494A1
申请日:
2018.12.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to frigostable compositions suitable for iontophoretic transdermal delivery of a triptan compound, comprising: - a salt of a triptan compound, preferably sumatriptan succinate, - a polyamine, - one or more dicarboxylic acids, - 0.5 to 10.0 wt.-% (based on the total weight of the composition) of one or more monocarboxylic acids, and - water or an aqueous solvent mixture. The invention further relates to the use of the composition as an integral component of an iontophoretic patch, preferably as an anodic reservoir of the patch.
