A tissue fastener, comprising: an elongated filament (202, 302, 402) having a leading end (288, 388, 488) and a trailing end (286, 386, 486)； a needle guide (288, 388, 488) disposed on the leading end； and a retention member (206, 306, 406) disposed on the trailing end, the retention member being configured to resist advancement through at least one of a tissue and a prosthetic material.
