KOSHIO, HIROYUKI,ASAI, NORIO,TAKAHASHI, TAISUKE,SHIMIZU, TAKAFUMI,NAGAI, YASUHITO,KAWABATA, KEIKO,THOR, KARL BRUCE
申请号：
CA2792918
公开号：
CA2792918C
申请日:
2011.03.11
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed are compounds which are useful as therapeutics or prophylacticagents for diseases associated with 5-HT2c receptor, especially for urinaryincontinence such as stress urinary incontinence, urge urinary incontinenceand mixedurinary incontinence, and the like. Studies have been made on these compoundswhich have a 5-HT2c receptor agonist action and are thus useful as activeingredientsof pharmaceutical compositions for the treatment or prophylaxis of urinaryincontinence such as stress urinary incontinence, urge urinary incontinenceand mixedurinary incontinence, and the like, and it is confirmed that these specificbenzazepinecompound have an excellent 5-HT2c receptor agonist action. An example of oneof thecompounds is as follows:(see above formula)
